Aim: To demonstrate the potential of in-line nanoparticle size measurements using the NanoFlowSizer (NFS) as a PAT method. To achieve real-time process control by establishing automated regulation of ...

Technological innovations throughout the past several decades have transformed the pharmaceutical manufacturing process from traditional batch production to ...

Advances in process analytical technology have been achieved, but significant challenges remain. Continuous API manufacturing has the potential to provide tremendous benefits to the pharmaceutical ...

This article overviews some of the benefits and methods of state-based control as it applies to the models defined by the ISA106, Procedure Automation for Continuous Process Operations standards ...

Advances in equipment, instrument, and control systems are enabling online monitoring of continuous API manufacturing. Continuous API manufacturing has the potential to provide tremendous benefits to ...

In biopharmaceutical manufacturing, consistency is vital but hard to achieve. Turning raw materials into safe, high-quality medicines requires stable processes. However, the living cellular expression ...

The extent to which products meet specifications needs to be systematically monitored in a production process. Product quality will typically be defined by two quantities: deviations from stated ...

The oil and gas industry involves capital intensive processes with continuous output. Raw materials, such as crude oil, are converted to petroleum products on a very large-scale, making process ...