Scientists create the most detailed digital simulation of life ever attempted

A remarkably small bacterium containing fewer than 500 genes serves as the basis for one of the most detailed digital life ...

Why simulating an entire cell cycle took years, multiple GPUs and six days per run

By simulating the life cycle of a minimal bacterial cell—from DNA replication to protein translation to metabolism and cell ...
ucdavis.edu

Computational Model Uses Language Theory to Predict DNA Shapes That Underlie Gene Expression and Disease

R-loops are structures that form when a strand of RNA (red) forms a stable structure with double-stranded DNA, causing one strand of the DNA to form a loop. R-loops are associated with gene ...
Nanowerk

First computer simulation that captures every molecule in a living cell through its full life cycle (w/video)

By simulating the life cycle of a minimal bacterial cell, from DNA replication to protein translation to metabolism and cell division, scientists have opened a new frontier of computer vision into the ...
Kaleido Scope

New model for replication of BKPyV virus, a major cause of kidney transplant failure

To better understand BKPyV replication and ways to prevent it, researchers in the UAB Department of Microbiology have published a single-cell analysis of BKPyV infection in primary kidney cells. Their ...
Science Daily

Cracking the code of life: new AI model learns DNA's hidden language

With GROVER, a new large language model trained on human DNA, researchers could now attempt to decode the complex information hidden in our genome. GROVER treats human DNA as a text, learning its ...
News Medical

DNA language model performance hinges on pre-training data choices

Researchers at The University of Texas MD Anderson Cancer Center have performed a comprehensive evaluation of five artificial intelligence (AI) models trained on genomic sequences, known as DNA ...