The team first created mice that lacked a key iron accumulation gene in the gonadal cells of XY embryos during the period of sex determination. These embryos had higher levels of DNA methylation, ...

A surprising finding from researchers in Japan has shown how an environmental factor can influence the development of sex organs in unborn mice. The discovery challenges the longstanding belief that ...

Researchers at the University of Toronto have mapped the spatial distribution of around 700 long non-coding RNAs, otherwise known as lncRNAs, in the testes. The team discovered much higher levels of ...

A new study in Nature shows that when pregnant mice don’t have enough iron, their (usually male) fetuses with a Y sex chromosome sometimes develop ovaries instead of testes. In other words, ...