Using human liver samples and a mouse model of cirrhosis, researchers identified epigenetic overactivation of the inflammatory PAF–PAF-R pathway in hepatic macrophages as a key driver of liver damage.

Until now, doctors knew hepatic stellate cells mainly as drivers of liver fibrosis. The actual functions of this cell type have hardly been studied to date. Researchers have now determined that ...

Fats are an important part of the human diet as a major source of energy. Around 90% of the fat stores are on top of muscle, so just under the skin. However, excessive dietary fat intake leads to fat ...

Chronic liver disease gets worse when the liver's immune system stays overactive, resulting in ongoing inflammation and scarring. Signals from the gut make the situation worse by encouraging immune ...

If you are generally healthy, your body does not need a reset as the liver works best with time and consistency, meaning fewer repeated stresses and enough recovery time to heal and function properly ...

A new discovery about how the liver flushes cholesterol from the body could lead to more effective treatments for cardiovascular disease – the leading cause of death worldwide. University of Leeds ...

Some high-dose detox “natural” supplements, such as green tea extract, can lead to liver inflammation, reflected in elevated ...

Every January, the same wave of "detox" promises rolls in. Juice cleanses, detox teas, charcoal capsules and liver "resets" all sell a familiar story: you overdid it over Christmas, your body is full ...