A study published in the Proceedings of the National Academy of Sciences by scientists from Israel and Ghana shows that an evolutionarily significant mutation in the human APOL1 gene arises not ...

The study of experimental evolution in Escherichia coli has provided unprecedented insights into the mechanisms of adaptive mutations, elucidating how populations diverge and optimise their fitness ...

Knowing how human DNA changes over generations is essential to estimating genetic disease risks and understanding how we evolved. But some of the most changeable regions of our DNA have been ...

The search space for protein engineering grows exponentially with complexity. A protein of just 100 amino acids has 20100 ...

This study presents a valuable finding on the mutational order for common alterations in colorectal cancer. The evidence of in vitro growth assays comparing mutations is solid, although inclusion of ...

A new study using serial liquid biopsies to track how metastatic prostate cancer evolves under treatment pressure showed that ...

This study reclassified patients according to modern WHO Classification criteria by integrating multi-dimensional molecular markers. It thoroughly investigated the clinical and molecular disparities ...

Liquid biopsy encompasses a variety of molecular approaches to detect circulating tumor DNA (ctDNA) and has become a powerful tool in the diagnosis and treatment of solid tumors. Current applications ...

A groundbreaking study published in this week’s issue of PNAS by scientists from Israel and Ghana shows that an evolutionarily significant mutation in the human APOL1 gene arises not randomly but more ...