Mutations in the tumor suppressor TP53 are a common cause of cancer, making the altered protein an attractive target for ...

Many people are familiar with histamine, a biological molecule that serves as a key driver of allergic reactions and other ...

A new single-cell profiling technique has mapped pre-malignant gene mutations and their effects in solid tissues for the ...

A study demonstrates that the 'previous state' of blood stem cells plays a decisive role in the subtype of leukemia that develops. The new technique, called STRACK, allows monitoring of the evolution ...

Researchers developed a single-cell sequencing method that simultaneously measures cancer-linked DNA mutations and gene ...

Unstable proteins are the main drivers of many different heritable diseases, according to a new study, including genetic disorders responsible for the formation of cataracts, and different types of ...

A common mutation in the KRAS gene is associated with improved overall survival in pancreatic ductal adenocarcinoma (PDAC) compared with other variants, in part because the mutation appears to lead to ...

Patients with BRCA-mutant breast cancer had a significantly higher risk of breast implant-associated anaplastic large-cell lymphoma (BIA-ALCL), a large cohort study showed. BRCA1/2 mutations conferred ...