The ribosome, that protein-making machine, relies on other, smaller machines. For example, it works in concert with a mechanism that supplies amino-acid-carrying tRNAs, including tRNAs that require ...
A groundbreaking study has shed light on the critical role of a tRNA methylation enzyme, TRMT10A, in supporting brain function. The findings reveal how the absence of TRMT10A leads to a reduction in ...
Archaeosine is synthesized via three steps in tRNA. ArcS, the second-step enzyme, transfers a lysine to preQ 0, which is introduced into tRNA by ArcTGT, the first-step enzyme. The resultant preQ 0-Lys ...
A tRNA that recognizes the codon for tryptophan and delivers this amino acid to the ribosome. (Note 5) 2′-O-methylcytidine (Cm): A modified nucleoside in which the 2′-OH group of the ribose in ...
Suggested Citation: "2 Importance and Impacts of RNA Modifications in Biology, Disease, Medicine, and Society." National Academies of Sciences, Engineering, and Medicine. 2024. Charting a Future for ...
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