AZoLifeSciences on MSN
Overcoming endosomal escape in oligonucleotide drug delivery
This study addresses endosomal escape in oligonucleotide therapies and how engineered peptides can enhance intracellular drug delivery efficiency.
Image-based high-content screening enables drug discovery by quantifying cellular changes. With growing use of 3D spheroid ...
This review provides a comprehensive overview of the latest advances in droplet microfluidics, with a particular focus on its ...
A clinical psychology specialist warned of “oversimplification” as he offered additional context to a claim that gang ...
Focusing on the establishment of Sino Biological‘s Center for Bioprocessing (C4B) in Houston, it highlights how the ...
AZoLifeSciences on MSN
Engineered human skin acts as a living biosensor for inflammation
Implanted living skin-based biosensors offer a breakthrough in inflammation tracking, providing real-time biomarker monitoring without invasive procedures.
Small-molecule mitochondrial transcription factor A modulators stabilize mtDNA, preventing cytosolic escape and suppressing cGAS-STING interferon signaling, while improving bioenergetics and fibrosis ...
BACKGROUND: The disruption of the blood–brain barrier (BBB) is a central pathogenic event in many central nervous system disorders. However, the mechanisms regulating BBB function remain incompletely ...
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