What is COBOL, the high-level programming language that is behind biggest-ever fall in IBM stock value

AI startup Anthropic's claim of automating COBOL modernization sent IBM's stock plummeting, wiping billions off its market value. The decades-old language, still powering critical systems, faces a ...
eLife

A proteome-wide biochemical screen defines binding determinants of the core autophagy protein LC3B

Human MAP1LC3B (LC3B) binds proteins involved in autophagy and other cellular processes using a degenerate four-residue short linear motif known as the LC3-interacting region (LIR). Biochemical and ...
eLife

TAD boundary architecture and gene activity are uncoupled

A proposed function of TADs is to contribute to gene regulation by promoting chromatin interactions within a TAD and by suppressing interactions between TADs. Here, we directly probe the ...
Investopedia

Placed-in-Service: Definition and Significance for Assets

Will Kenton is an expert on the economy and investing laws and regulations. He previously held senior editorial roles at Investopedia and Kapitall Wire and holds a MA in Economics from The New School ...
Nature

Could SAP depletion stabilize Alzheimer disease?

Serum amyloid P component (SAP; Figure 1) is normally present in plasma and cerebrospinal fluid, and also occurs in the amyloid plaques and neurofibrillary tangles that form the main brain lesions of ...