Nature

First-of-a-kind stem cell therapies set for approval in Japan

Regenerative medicines are headed for people with Parkinson’s disease or severe heart failure — but researchers are concerned about minimal clinical-trial data.
The Chosun Ilbo

Japan Approves World's First iPS Therapies for Parkinson's, Heart Failure

Japan Approves Worlds First iPS Therapies for Parkinsons, Heart Failure Conditional approval granted for Sumitomo Pharmas ...
eLife

SETDB1 enables development beyond cleavage stages by extinguishing the MERVL-driven two-cell totipotency transcriptional program in the mouse embryo

Conditional genetics and single-embryo RNA-seq show that SETDB1 extinguishes the transient, retroelement-driven transcriptional programs of the totipotent two-cell state to facilitate the exit from ...
MIT Technology Review

The first human test of a rejuvenation method will begin “shortly”

In a bid to treat blindness, Life Biosciences will try out potent cellular reprogramming technology on volunteers. When Elon Musk was at Davos last week, an interviewer asked him if he thought aging ...
Medical Xpress

T cells gain superior memory through new reprogramming method, boosting cancer-fighting abilities

Georgetown University's Lombardi Comprehensive Cancer Center researchers have identified a new way to reprogram T cells, which are infection and tumor-fighting white blood cells, so that they have a ...
Los Angeles Times

Reprogramming camp for immune cells shows early promise for autoimmune diseases

This is read by an automated voice. Please report any issues or inconsistencies here. Scientists are trying a revolutionary new approach to treat rheumatoid arthritis, multiple sclerosis, lupus and ...
Business Wire

Junevity Expands Seed Funding to $20 Million for Cell Reprogramming with siRNA

New funding led by Goldcrest Capital and Godfrey Capital to advance lead candidate JUN_01 for type 2 diabetes and obesity to first-in-human studies JUN_01 would be the first ever candidate to ...
Virtualization Review

Expert Explains Conditional Access and Zero Trust Implementation in Microsoft Entra

At today's online summit hosted by RedmondMag, titled "Cloud Control: Securing Access and Identity in the Microsoft SaaS Stack," longtime Microsoft MVP and Principal Cloud Architect Joey D'Antoni ...
Observer

This Longevity Startup Is Bringing Anti-Aging Gene Therapy to Human Trials

Boston-based Life Biosciences is testing whether reprogramming human cells can slow or even reverse the effects of aging. Unsplash Life Biosciences, a Boston-based biotechnology company founded in ...
The American Journal of Managed Care

Metabolic Reprogramming Takes Center Stage in Fibrotic Lung Disease

Metabolic reprogramming in fibrotic lung diseases involves key metabolites like lactate, succinate, and 2-hydroxyglutarate, driving inflammation and fibroblast activation. Lactate accumulation ...
Labroots

Cell Reprogramming as an Approach to Cancer Therapy

Cancer immunotherapy has advanced the field of medicine and cancer care. Specifically, immunotherapy refers to the targeted treatment of the immune system. Over the last few decades, immunotherapy has ...