In biology, reprogramming refers to erasure and remodeling of epigenetic marks, such as DNA methylation, during mammalian development or in cell culture. [1] Such control is also often …

Apr 9, 2025 · This review summarizes the recent advances in cell reprogramming mediated by transcription factors or chemical molecules, followed by elaborating on the important roles of …

Dec 17, 2025 · Cell reprogramming is the process of reverting mature, specialised cells into induced pluripotent stem cells. Reprogramming also refers to the erasure and re-establishment of epigenetic …

Jan 12, 2026 · Abstract Cellular reprogramming, a method of “resetting” the epigenetic clock by reversing the differentiation state of cells, has emerged as a promising approach to anti-aging, …

To return an adult cell to a stem cell state, scientists package a stretch of DNA (called a plasmid) that carries the reprogramming instructions with a solution of lipids that help it melt through the cell …

Feb 5, 2025 · Therapeutic reprogramming represents a transformative paradigm in regenerative medicine, developing new approaches in cell therapy, small molecule drugs, biologics, and gene …

Jul 31, 2025 · Learn about the intricate science of cell reprogramming, a process that redefines biological possibilities for health and discovery.

Jun 1, 2025 · Chemical reprogramming uniquely enhances the plasticity of human somatic cells, reverting them to progenitor states through dedifferentiation, thereby offering a potential innovative …

“By attempting to reprogram a population of progenitor cells, you have a way to increase efficiency,” Hochedlinger said. Approximately 300 cells out of 1,000 successfully transform into an iPS cell by …

Dec 2, 2025 · While the terms sound and look very similar, there is an important distinction. Cell reprogramming is the act of reverting mature, specialised cells into induced pluripotent stem cells, …